Chadwick's sign is a bluish discoloration of the cervix, vagina, and labia caused by the hormone estrogen which results in venous congestion. It can be observed as early as 6-8 weeks after conception[1], and its presence is an early sign of pregnancy.
These color changes were discovered in approximately 1836 by French doctor Étienne Joseph Jacquemin (1796-1872),[2] and are named after James Read Chadwick, who drew attention to it in a paper read before the American Gynecological Society in 1886 and published in the following year, wherein he credited Jacquemin for their discovery.[2][3]
|
|||||||||||||||||